Supplementary Materials

Supplementary Material for:

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

Yuxuan Wang, Simeon Springer, Carolyn L. Mulvey, Natalie Silliman, Joy Schaefer, Mark Sausen, Nathan James, Eleni M. Rettig, Theresa Guo, Curtis R. Pickering, Justin A. Bishop, Christine H. Chung, Joseph A. Califano, David W. Eisele, Carole Fakhry, Christine G. Gourin, Patrick K. Ha, Hyunseok Kang, Ana Kiess, Wayne M. Koch, Jeffrey N. Myers, Harry Quon, Jeremy D. Richmon, David Sidransky, Ralph P. Tufano, William H. Westra, Chetan Bettegowda, Luis A. Diaz Jr., Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein,* Nishant Agrawal*

*Corresponding author. E-mail: nagrawal{at}jhmi.edu (N.A.); vogelbe{at}jhmi.edu (B.V.)

Published 24 June 2015, Sci. Transl. Med. 7, 293ra104 (2015)
DOI: 10.1126/scitranslmed.aaa8507

This PDF file includes:

  • Fig. S1. Tumor DNA is detectable in the saliva of patients before recurrence becomes clinically evident.
  • Fig. S2. Patients with undetectable tumor DNA after surgery have better disease-free survival.
  • Legends for tables S1 to S3

[Download PDF]

Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Patient demographics.
  • Table S2 (Microsoft Excel format). Primer sequences used in multiplex assay for identification of driver mutations in tumors.
  • Table S3 (Microsoft Excel format). Amounts of tumor-derived DNA in saliva and plasma.

[Download Tables S1 to S3]