Supplementary Materials

Supplementary Material for:

mAbs and Ad-Vectored IFN-α Therapy Rescue Ebola-Infected Nonhuman Primates When Administered After the Detection of Viremia and Symptoms

Xiangguo Qiu, Gary Wong, Lisa Fernando, Jonathan Audet, Alexander Bello, Jim Strong, Judie B. Alimonti, Gary P. Kobinger*

*Corresponding author. E-mail: Gary.Kobinger@phac-aspc.gc.ca

Published 16 October 2013, Sci. Transl. Med. 5, 207ra143 (2013)
DOI: 10.1126/scitranslmed.3006605

This PDF file includes:

  • Fig. S1. EBOV/May-eGFP–neutralizing antibody assays.
  • Fig. S2. Survival curves and time to death of historical control rhesus and cynomolgus macaques.
  • Table S1. Ebola viremia values at various times post-challenge as measured by qRT-PCR.
  • Table S2. Viremia by TCID50.
  • Table S3. Clinical score.
  • Table S4. Temperature.
  • Table S5. ALT.
  • Table S6. ALP.
  • Table S7. PLT.
  • Table S8. WBCs.
  • Table S9. PCR results for animal C4 for EBOV and 16S DNA.
  • Table S10. IgM titers.
  • Table S11. IgG titers.
  • Table S12. nAb titers.
  • Table S13. ELISpot counts.
  • Table S14. Cytokine positivity of CD8+ cells.
  • Table S15. Cytokine positivity of CD8+ CD107a+ cells.
  • Table S16. Cytokine positivity of CD8+ IL-2+ cells.
  • Table S17. Cytokine positivity of CD8+ IFN-γ+ cells.
  • Table S18. Cytokine positivity of CD8+ IL-4+ cells.
  • Table S19. Cytokine positivity of CD4+ cells.
  • Table S20. Cytokine positivity of CD4+ CD107a+ cells.
  • Table S21. Cytokine positivity of CD4+ IL-2+ cells.
  • Table S22. Cytokine positivity of CD4+ IFN-γ+ cells.
  • Table S23. Cytokine positivity of CD4+ IL-4+ cells.

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