Research ArticleCancer

Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways

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Science Translational Medicine  25 Oct 2017:
Vol. 9, Issue 413, eaao1214
DOI: 10.1126/scitranslmed.aao1214

Article Information

vol. 9 no. 413

PubMed: 
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History: 
  • Received for publication June 15, 2017
  • Accepted for publication September 25, 2017

Author Information

  1. Yoriko Saito1,
  2. Yoshiki Mochizuki2,
  3. Ikuko Ogahara1,
  4. Takashi Watanabe2,
  5. Leah Hogdal3,
  6. Shinsuke Takagi4,
  7. Kaori Sato1,
  8. Akiko Kaneko1,
  9. Hiroshi Kajita1,
  10. Naoyuki Uchida4,
  11. Takehiro Fukami5,
  12. Leonard D. Shultz6,
  13. Shuichi Taniguchi4,
  14. Osamu Ohara2,7,
  15. Anthony G. Letai3 and
  16. Fumihiko Ishikawa1,*
  1. 1Laboratory for Human Disease Models, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan.
  2. 2Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan.
  3. 3Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  4. 4Department of Hematology, Toranomon Hospital, Tokyo 105-8470, Japan.
  5. 5RIKEN Program for Drug Discovery and Medical Technology Platforms, Yokohama, Kanagawa 230-0045, Japan.
  6. 6The Jackson Laboratory, Bar Harbor, ME 04609, USA.
  7. 7Kazusa DNA Research Institute, Kisarazu, Chiba 292-0818, Japan.
  1. *Corresponding author. Email: fumihiko.ishikawa{at}riken.jp

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