Research ArticleBIOMATERIALS

Engineering a highly elastic human protein–based sealant for surgical applications

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Science Translational Medicine  04 Oct 2017:
Vol. 9, Issue 410, eaai7466
DOI: 10.1126/scitranslmed.aai7466

Article Information

vol. 9 no. 410

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  • Received for publication August 6, 2016
  • Resubmitted May 11, 2017
  • Accepted for publication August 17, 2017

Author Information

  1. Nasim Annabi1,2,3,4,*,
  2. Yi-Nan Zhang2,3,,
  3. Alexander Assmann2,3,4,5,
  4. Ehsan Shirzaei Sani1,
  5. George Cheng6,
  6. Antonio D. Lassaletta6,
  7. Andrea Vegh2,3,
  8. Bijan Dehghani2,3,
  9. Guillermo U. Ruiz-Esparza2,3,
  10. Xichi Wang2,3,
  11. Sidhu Gangadharan6,
  12. Anthony S. Weiss7,8,9 and
  13. Ali Khademhosseini2,3,4,10,*
  1. 1Department of Chemical Engineering, Northeastern University, Boston, MA 02115–5000, USA.
  2. 2Biomaterials Innovation Research Center, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02139, USA.
  3. 3Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  4. 4Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  5. 5Department of Cardiovascular Surgery and Research Group for Experimental Surgery, Heinrich Heine University, Medical Faculty, Duesseldorf 40225, Germany.
  6. 6Division of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  7. 7School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales 2006, Australia.
  8. 8Charles Perkins Centre, University of Sydney, Sydney, New South Wales 2006, Australia.
  9. 9Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia.
  10. 10Department of Physics, King Abdulaziz University, Jeddah 21569, Saudi Arabia.
  1. *Corresponding author. Email: n.annabi{at} (N.A.); alik{at} (A.K.)
  • Present address: Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON M5S 3G9, Canada.


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Article usage: October 2017 to March 2018

Oct 2017227428371245
Nov 20172080142218
Dec 2017144877118
Jan 2018109776126
Feb 2018132181124
Mar 201810923761