Research ArticleCancer

Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma

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Science Translational Medicine  13 Sep 2017:
Vol. 9, Issue 407, eaal4712
DOI: 10.1126/scitranslmed.aal4712

Article Information

vol. 9 no. 407

Print ISSN: 
Online ISSN: 
  • Received for publication November 24, 2016
  • Resubmitted May 30, 2017
  • Accepted for publication July 11, 2017

Author Information

  1. Manuel Fankhauser1,*,
  2. Maria A. S. Broggi1,2,*,
  3. Lambert Potin1,2,
  4. Natacha Bordry3,
  5. Laura Jeanbart1,
  6. Amanda W. Lund1,4,
  7. Elodie Da Costa1,
  8. Sylvie Hauert1,2,
  9. Marcela Rincon-Restrepo1,
  10. Christopher Tremblay1,
  11. Elena Cabello5,
  12. Krisztian Homicsko3,6,
  13. Olivier Michielin3,
  14. Douglas Hanahan6,
  15. Daniel E. Speiser3 and
  16. Melody A. Swartz1,2,6,7,
  1. 1Institute of Bioengineering, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland.
  2. 2Institute for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
  3. 3Department of Oncology and Ludwig Cancer Research, University of Lausanne, Lausanne, Switzerland.
  4. 4Department of Cell, Developmental and Cancer Biology and Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA.
  5. 5The Bioinformatics and Biostatistics Core Facility, EPFL, Lausanne, Switzerland.
  6. 6Swiss Institute for Experimental Cancer Research, School of Life Sciences, EPFL, Lausanne, Switzerland.
  7. 7The Ben May Department for Cancer Research, University of Chicago, Chicago, IL 60637, USA.
  1. Corresponding author. Email: melodyswartz{at}
    • * These authors contributed equally to this work.


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    Article usage: September 2017 to November 2017

    Sep 201785395051173
    Oct 20171063132340
    Nov 201741876121