Research ArticleMetabolic Disease

Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin’s glucose-lowering effects

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Science Translational Medicine  13 Sep 2017:
Vol. 9, Issue 407, eaad4000
DOI: 10.1126/scitranslmed.aad4000

Article Information

vol. 9 no. 407

PubMed: 
Print ISSN: 
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History: 
  • Received for publication July 6, 2015
  • Resubmitted January 30, 2017
  • Accepted for publication August 10, 2017

Author Information

  1. Cheol Hwangbo1,*,
  2. Jingxia Wu1,*,
  3. Irinna Papangeli1,
  4. Takaomi Adachi1,
  5. Bikram Sharma2,
  6. Saejeong Park1,
  7. Lina Zhao1,
  8. Hyekyung Ju1,
  9. Gwang-woong Go1,
  10. Guoliang Cui3,
  11. Mohammed Inayathullah4,
  12. Judith K. Job4,
  13. Jayakumar Rajadas4,
  14. Stephanie L. Kwei5,
  15. Ming O. Li6,
  16. Alan R. Morrison1,
  17. Thomas Quertermous7,
  18. Arya Mani1,
  19. Kristy Red-Horse2 and
  20. Hyung J. Chun1,
  1. 1Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT 06511, USA.
  2. 2Department of Biology, Stanford University, Stanford, CA 94304, USA.
  3. 3Department of Immunobiology, Yale School of Medicine, New Haven, CT 06511, USA.
  4. 4Biomaterials and Advanced Drug Delivery Laboratory, Stanford University, Stanford, CA 94304, USA.
  5. 5Section of Plastic and Reconstructive Surgery, Yale School of Medicine, New Haven, CT 06511, USA.
  6. 6Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  7. 7Division of Cardiovascular Medicine, Stanford University, Stanford, CA 94304, USA.
  1. Corresponding author. Email: hyung.chun{at}yale.edu
    • * These authors contributed equally to this work.

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