FocusALLERGY

Pinning allergies on pathogenic TH2 cells

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Science Translational Medicine  02 Aug 2017:
Vol. 9, Issue 401, eaao0392
DOI: 10.1126/scitranslmed.aao0392

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Abstract

A new proinflammatory subtype of antigen-specific TH2 cell that expresses CD161 emerges as the pathogenic cell type in allergic disease and is deleted during allergen-specific immunotherapy (Wambre et al., this issue).

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