Research ArticleNEUROBIOLOGY

Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica

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Science Translational Medicine  05 Jul 2017:
Vol. 9, Issue 397, eaai9111
DOI: 10.1126/scitranslmed.aai9111

Article Information

vol. 9 no. 397

PubMed: 
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History: 
  • Received for publication August 30, 2016
  • Accepted for publication May 19, 2017

Author Information

  1. Fumitaka Shimizu1,*,
  2. Kristin L. Schaller2,*,
  3. Gregory P. Owens2,
  4. Anne C. Cotleur3,
  5. Debra Kellner3,
  6. Yukio Takeshita1,
  7. Birgit Obermeier3,
  8. Thomas J. Kryzer4,
  9. Yasuteru Sano1,
  10. Takashi Kanda1,
  11. Vanda A. Lennon4,
  12. Richard M. Ransohoff3, and
  13. Jeffrey L. Bennett2,
  1. 1Department of Neurology and Clinical Neuroscience, Yamaguchi University Graduate School of Medicine, Minamikogushi, Ube, Yamaguchi 7558505, Japan.
  2. 2Departments of Neurology and Ophthalmology, Program in Neuroscience, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA.
  3. 3Neuroimmunology and Acute Neurology, Biogen, Cambridge, MA 02142, USA.
  4. 4Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
  1. Corresponding author. Email: richard.ransohoff{at}biogen.com (R.M.R.); jeffrey.bennett{at}ucdenver.edu (J.L.B.)
    • * These authors contributed equally to this work.

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