Editors' ChoiceBONE DISORDERS

Strengthening brittle bones

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Science Translational Medicine  28 Jun 2017:
Vol. 9, Issue 396, eaan6730
DOI: 10.1126/scitranslmed.aan6730

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Abstract

Decreased WNT1 signaling weakens bones but is partially reversed by blocking the WNT1 inhibitory regulator sclerostin.

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