Research ArticleDiabetes

Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes

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Science Translational Medicine  14 Jun 2017:
Vol. 9, Issue 394, eaah4477
DOI: 10.1126/scitranslmed.aah4477

Article Information

vol. 9 no. 394

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  • Received for publication June 28, 2016
  • Resubmitted February 23, 2017
  • Accepted for publication May 5, 2017

Author Information

  1. Annika S. Axelsson1,
  2. Emily Tubbs1,
  3. Brig Mecham2,
  4. Shaji Chacko3,
  5. Hannah A. Nenonen1,
  6. Yunzhao Tang1,
  7. Jed W. Fahey4,
  8. Jonathan M. J. Derry5,
  9. Claes B. Wollheim1,6,
  10. Nils Wierup1,
  11. Morey W. Haymond3,
  12. Stephen H. Friend5,
  13. Hindrik Mulder1 and
  14. Anders H. Rosengren1,5,7,*
  1. 1Department of Clinical Sciences, Lund University Diabetes Center, Malmö, SE-20502 Malmö, Sweden.
  2. 2Trialomics, Seattle, WA 98115, USA.
  3. 3U.S. Department of Agriculture/Agricultural Research Service, Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  4. 4Departments of Medicine, Pharmacology and Molecular Sciences, and International Health, and Cullman Chemoprotection Center, Johns Hopkins University, Baltimore, MD 21205, USA.
  5. 5Sage Bionetworks, 1100 Fairview Avenue North, Seattle, WA 98109, USA.
  6. 6Department of Cell Physiology and Metabolism, University Medical Center, CH-1211 Geneva, Switzerland.
  7. 7Institute of Neuroscience and Physiology, University of Gothenburg, SE-40530 Göteborg, Sweden.
  1. *Corresponding author. Email: anders.rosengren{at}


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