Editors' ChoiceCancer

A new therapeutic target for myelofibrosis is cause for Gli

+ See all authors and affiliations

Science Translational Medicine  31 May 2017:
Vol. 9, Issue 392, eaan4297
DOI: 10.1126/scitranslmed.aan4297

You are currently viewing the abstract.

View Full Text

Abstract

Myeloproliferative neoplasm cells recruit Gli1 positive mesenchymal stromal cells to transdifferentiate into fibrosis-causing myofibroblasts, a process that can be inhibited by a Gli inhibitor.

View Full Text