Research ArticleNanomedicine
Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts
- Miles A. Miller1,2,
- Ravi Chandra1,3,
- Michael F. Cuccarese1,
- Christina Pfirschke1,
- Camilla Engblom1,
- Shawn Stapleton1,
- Utsarga Adhikary1,
- Rainer H. Kohler1,
- James F. Mohan1,
- Mikael J. Pittet1,2 and
- Ralph Weissleder1,2,4,*
- 1Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge Street, CPZN 5206, Boston, MA 02114, USA.
- 2Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
- 3Harvard Radiation Oncology Program, 55 Fruit Street, Boston, MA 02114, USA.
- 4Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.
- ↵*Corresponding author. Email: rweissleder{at}mgh.harvard.edu
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Science Translational Medicine 31 May 2017:
Vol. 9, Issue 392, eaal0225
DOI: 10.1126/scitranslmed.aal0225
