Research ArticleHeart Failure

Central-acting therapeutics alleviate respiratory weakness caused by heart failure–induced ventilatory overdrive

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Science Translational Medicine  17 May 2017:
Vol. 9, Issue 390, eaag1303
DOI: 10.1126/scitranslmed.aag1303

Article Information

vol. 9 no. 390

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Online ISSN: 
  • Received for publication May 12, 2016
  • Accepted for publication March 13, 2017

Author Information

  1. Andrew J. Foster1,*,
  2. Mathew J. Platt1,*,
  3. Jason S. Huber1,
  4. Ashley L. Eadie2,
  5. Alicia M. Arkell1,
  6. Nadya Romanova1,
  7. David C. Wright1,
  8. Todd E. Gillis3,
  9. Coral L. Murrant1,
  10. Keith R. Brunt2, and
  11. Jeremy A. Simpson1,
  1. 1Department of Human Health and Nutritional Science, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
  2. 2Department of Pharmacology, Dalhousie Medicine, Saint John, New Brunswick E2L 4L5, Canada.
  3. 3Department of Integrative Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
  1. Corresponding author. Email: jeremys{at} (J.A.S.); keith.brunt{at} (K.R.B.)
    • * These authors contributed equally to this work.


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