Editors' ChoiceBONE FORMATION

“TrkA”cking why “no pain, no gain” is the rule for bone formation

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Science Translational Medicine  10 May 2017:
Vol. 9, Issue 389, eaan3780
DOI: 10.1126/scitranslmed.aan3780

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Abstract

Peripheral sensory nerves expressing TrkA innervate long bones and stimulate bone formation through the Wnt/β-catenin pathway when placed under stress.

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