Editors' ChoiceRheumatoid Arthritis

Macrophages take rheumatoid arthritis up a “Notch”

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Science Translational Medicine  29 Mar 2017:
Vol. 9, Issue 383, eaan3022
DOI: 10.1126/scitranslmed.aan3022

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Notch signaling in bone marrow–derived inflammatory macrophages is central to synovial inflammation seen in rheumatoid arthritis, representing a promising future therapeutic target.

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