Editors' ChoiceAlzheimer’s Disease

Modeling Alzheimer’s disease in mice with human neurons

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Science Translational Medicine  15 Mar 2017:
Vol. 9, Issue 381, eaam9867
DOI: 10.1126/scitranslmed.aam9867

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Abstract

Human neurons transplanted into a mouse model for Alzheimer’s disease show human-specific vulnerability to β-amyloid plaques and may help to identify new therapeutic targets.

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