Editors' ChoiceCancer

Beware! Are bacteria raising your oxidative stress?

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Science Translational Medicine  22 Feb 2017:
Vol. 9, Issue 378, eaam6066
DOI: 10.1126/scitranslmed.aam6066

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Abstract

Peptostreptococcus anaerobius, enriched in patients with colon cancer, induces cellular proliferation and dysplasia by toll-like receptor (TLR) 2– and TLR4-dependent increase in oxidative stress and cholesterol biosynthesis.

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