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Two-step enhanced cancer immunotherapy with engineered Salmonella typhimurium secreting heterologous flagellin

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Science Translational Medicine  08 Feb 2017:
Vol. 9, Issue 376, eaak9537
DOI: 10.1126/scitranslmed.aak9537

Article Information

vol. 9 no. 376

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 20, 2016
  • Resubmitted November 16, 2016
  • Accepted for publication December 2, 2016

Author Information

  1. Jin Hai Zheng1,2,
  2. Vu H. Nguyen1,3,
  3. Sheng-Nan Jiang4,5,
  4. Seung-Hwan Park6,
  5. Wenzhi Tan7,
  6. Seol Hee Hong8,
  7. Myung Geun Shin9,
  8. Ik-Joo Chung10,
  9. Yeongjin Hong7,
  10. Hee-Seung Bom4,
  11. Hyon E. Choy2,7,
  12. Shee Eun Lee8,
  13. Joon Haeng Rhee2,7,* and
  14. Jung-Joon Min1,2,4,7,*
  1. 1Laboratory of In Vivo Molecular Imaging, Institute for Molecular Imaging and Theranostics, Chonnam National University Hwasun Hospital, Jeonnam 58128, Republic of Korea.
  2. 2Department of Molecular Medicine (BrainKorea21 Plus), Chonnam National University Graduate School, Gwangju 61469, Republic of Korea.
  3. 3Department of Experimental Therapeutics, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
  4. 4Department of Nuclear Medicine, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.
  5. 5Department of Nuclear Medicine, Affiliated Haikou Hospital, Xiangya School of Medicine, Central South University, Hainan 570-208, China.
  6. 6Biological Resource Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Republic of Korea.
  7. 7Department of Microbiology and Clinical Vaccine R&D Center, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.
  8. 8Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea.
  9. 9Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.
  10. 10Department of Hemato-Oncology, Chonnam National University Medical School, Jeonnam 58128, Republic of Korea.
  1. *Corresponding author. Email: jjmin{at}jnu.ac.kr (J.-J.M.); jhrhee{at}chonnam.ac.kr (J.H.R.)

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