Research ArticleHIV

Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller

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Science Translational Medicine  18 Jan 2017:
Vol. 9, Issue 373, eaal2144
DOI: 10.1126/scitranslmed.aal2144

Article Information

vol. 9 no. 373

PubMed: 
Print ISSN: 
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History: 
  • Received for publication July 22, 2016
  • Resubmitted October 14, 2016
  • Accepted for publication December 8, 2016

Author Information

  1. Natalia T. Freund1,
  2. Haoqing Wang2,*,
  3. Louise Scharf2,*,,
  4. Lilian Nogueira1,
  5. Joshua A. Horwitz1,
  6. Yotam Bar-On1,
  7. Jovana Golijanin1,
  8. Stuart A. Sievers2,,
  9. Devin Sok3,
  10. Hui Cai4,
  11. Julio C. Cesar Lorenzi1,
  12. Ariel Halper-Stromberg1,
  13. Ildiko Toth5,
  14. Alicja Piechocka-Trocha5,
  15. Harry B. Gristick2,
  16. Marit J. van Gils6,
  17. Rogier W. Sanders6,
  18. Lai-Xi Wang4,
  19. Michael S. Seaman7,
  20. Dennis R. Burton3,5,
  21. Anna Gazumyan1,
  22. Bruce D. Walker5,8,
  23. Anthony P. West Jr2,
  24. Pamela J. Bjorkman2 and
  25. Michel C. Nussenzweig1,8,§
  1. 1Laboratory of Molecular Immunology, Rockefeller University, New York, NY 10065, USA.
  2. 2Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  3. 3Department of Immunology and Microbial Science, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, and International AIDS Vaccine Initiative Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.
  4. 4Department of Chemistry and Biochemistry, University of Maryland, 8051 Regents Drive, College Park, MD 20742, USA.
  5. 5Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02129, USA.
  6. 6Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
  7. 7Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  8. 8Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  1. §Corresponding author. Email: nussen{at}rockefeller.edu
    • * These authors contributed equally to this work.

    • Present address: 23andMe, Mountain View, CA 94041, USA.

    • Present address: Kite Pharma, Santa Monica, CA 90404, USA.

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