Technical CommentsInfectious Disease

Comment on “A small-molecule antivirulence agent for treating Clostridium difficile infection”

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Science Translational Medicine  21 Dec 2016:
Vol. 8, Issue 370, pp. 370tc2
DOI: 10.1126/scitranslmed.aad8926

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Abstract

New insights into the mechanism of action of ebselen, a small-molecule antivirulence agent that reduces disease pathology in a mouse model of Clostridium difficile infection, suggest a different molecular target may be responsible for its efficacy.

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