Research ArticleCARBON MONOXIDE POISONING

Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning

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Science Translational Medicine  07 Dec 2016:
Vol. 8, Issue 368, pp. 368ra173
DOI: 10.1126/scitranslmed.aah6571

Article Information

vol. 8 no. 368 368ra173

PubMed: 
Print ISSN: 
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History: 
  • Received for publication July 27, 2016
  • Accepted for publication November 16, 2016

Author Information

  1. Ivan Azarov1,*,
  2. Ling Wang1,2,*,
  3. Jason J. Rose1,2,*,
  4. Qinzi Xu1,
  5. Xueyin N. Huang1,
  6. Andrea Belanger3,
  7. Ying Wang2,
  8. Lanping Guo2,
  9. Chen Liu3,
  10. Kamil B. Ucer3,
  11. Charles F. McTiernan1,2,
  12. Christopher P. O’Donnell1,2,
  13. Sruti Shiva1,4,5,
  14. Jesús Tejero1,2,
  15. Daniel B. Kim-Shapiro3,6 and
  16. Mark T. Gladwin1,2,
  1. 1Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  2. 2Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA.
  3. 3Department of Physics, Wake Forest University, Winston-Salem, NC 27109, USA.
  4. 4Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  5. 5Center for Metabolism and Mitochondrial Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  6. 6Translational Science Center, Wake Forest University, Winston-Salem, NC 27109, USA.
  1. Corresponding author. Email: gladwinmt{at}upmc.edu
    • * These authors contributed equally to this work.

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