PerspectiveNeurodegenerative Disease

Neurodegeneration: From cellular concepts to clinical applications

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Science Translational Medicine  09 Nov 2016:
Vol. 8, Issue 364, pp. 364ps18
DOI: 10.1126/scitranslmed.aal2074

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Abstract

Developing therapies for neurodegenerative diseases will require new scientific approaches that take into account the detrimental effects of altered protein and RNA homeostasis on brain cells, the vulnerabilities of various organelles in certain diseases and aging neurons, and the complex multicellular interactions of the nervous system.

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