Vol 8, Issue 356
- Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression
T cells from diabetic individuals are hyperresponsive to IL-6 stimulation, which could contribute to disease pathogenesis and may be an avenue for therapeutic intervention.
A hydrogel drug delivery system allowed controlled, local delivery of ciprofloxacin across the tympanic membrane to treat acute otitis media in chinchillas.
Olyset Duo, a bed net treated with a mixture of the insecticides pyriproxyfen and permethrin, provides improved control of mosquito vectors of malaria in regions of high insecticide resistance.
A computer model of combination drug therapy improves predictive accuracy, requires less experimental data, and may reduce the barrier to developing multidrug regimens.