The Human Vaccines Project: A roadmap for cancer vaccine development

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Science Translational Medicine  13 Apr 2016:
Vol. 8, Issue 334, pp. 334ps9
DOI: 10.1126/scitranslmed.aaf0685

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Cancer vaccine development has been vigorously pursued for 40 years. Immunity to tumor antigens can be elicited by most vaccines tested, but their clinical efficacy remains modest. We argue that a concerted international effort is necessary to understand the human antitumor immune response and achieve clinically effective cancer vaccines.

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