Erratum

Erratum for the Research Article: “CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo” by P. J. Hanley, J. J. Melenhorst, S. Nikiforow, P. Scheinberg, J. W. Blaney, G. Demmler-Harrison, C. R. Cruz, S. Lam, R. A. Krance, K. S. Leung, C. A. Martinez, H. Liu, D. C. Douek, H. E. Heslop, C. M. Rooney, E. J. Shpall, A. J. Barrett, J. R. Rodgers, C. M. Bollard

Science Translational Medicine  13 Jan 2016:
Vol. 8, Issue 321, pp. 321er1
DOI: 10.1126/scitranslmed.aaf1718

In the manuscript “CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo,” as pointed out by a reader, Fig. 3F showed the avidity for T cells recognizing MLN from a CMV-seropositive donor as 0.2 ng/mL, but this should be 0.4 ng/mL as shown in Table 1. A recalculation of the fold-difference in avidity using only the paired samples and the arithmetic mean rather than the geometric mean yielded a result of 17-fold rather than 30-fold, as stated on page 3. In addition, a recalculation of the atypical vs. typical T cell receptor frequencies in fact showed a 60-fold difference as opposed to a 27-fold difference, as originally written in the discussion on page 7. The 27-fold difference originally stated actually refers to a calculation of the diversity of TCRs in table S2 and was not meant to be included in the discussion. None of these changes affect the overall conclusions of the study. The errors have been corrected in the PDF and HTML (full text) versions of the paper.

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