PerspectiveCancer

Targeting the glucocorticoid receptor in breast and prostate cancers

Science Translational Medicine  16 Sep 2015:
Vol. 7, Issue 305, pp. 305ps19
DOI: 10.1126/scitranslmed.aac7531

You are currently viewing the abstract.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Abstract

Steroid receptors for androgens and estrogens have essential roles in prostate and breast cancers. Recently, glucocorticoid receptor (GR) activity has also been proposed as having an important role in these cancers. Underscoring the cooperative nature of nuclear receptor activity, data now suggest that GR function in prostate and breast cancers is dependent on the tumor’s concomitant androgen or estrogen receptor activity.

View Full Text

Related Content