PerspectiveVaccines

Immunology of protection from Ebola virus infection

Science Translational Medicine  06 May 2015:
Vol. 7, Issue 286, pp. 286ps11
DOI: 10.1126/scitranslmed.aaa8202

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Abstract

A December 2014 meeting reviewed Ebola virus immunology relevant to vaccine development, including Ebola prevention, immunity, assay standardization, and regulatory considerations. Vaccinated humans appear to achieve immune responses comparable in magnitude with those associated with protection in nonhuman primates, suggesting that immunological data could be used to demonstrate vaccine efficacy.

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