FocusOrgan Transplantation

I spy alloreactive T cells

Science Translational Medicine  28 Jan 2015:
Vol. 7, Issue 272, pp. 272fs3
DOI: 10.1126/scitranslmed.aaa5083

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Abstract

High-throughput sequencing of the T cell receptor Vβ CDR3 region allowed longitudinal tracking of alloreactive T cells in kidney transplant patients, revealing clonal deletion as a mechanism of transplantation tolerance (Morris et al., this issue).

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