FocusDrug Development

The Host Battles Drug-Resistant Tuberculosis

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Science Translational Medicine  19 Nov 2014:
Vol. 6, Issue 263, pp. 263fs47
DOI: 10.1126/scitranslmed.aaa1274

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The repurposed drug metformin reduces unproductive inflammation, refocuses host immune responses on the infectious agent Mycobacterium tuberculosis, and thus may improve treatment outcomes for drug-resistant tuberculosis (Singhal et al., this issue).

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