Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates

Article Tools

• Email

  Thank you for your interest in spreading the word about Science Translational Medicine.

  NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

  Your Email

  Your Name

  Send To

  Enter multiple addresses on separate lines or separate them with commas.

  You are going to email the following Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates

  Message Subject (Your Name) has forwarded a page to you from Science Translational Medicine

  Message Body (Your Name) thought you would like to see this page from the Science Translational Medicine web site.

  Your Personal Message

  Send Message
• Download Powerpoint
• Print
• Save to my folders

  Log In with your AAAS Login

   

• Alerts

  Please log in to add an alert for this article.

  Log In with your AAAS Login

   

  Sign In to Email Alerts with your Email Address

  Email

  Log in
• Citation tools

  Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates

  By Y. Joy Yu, Jasvinder K. Atwal, Yin Zhang, Raymond K. Tong, Kristin R. Wildsmith, Christine Tan, Nga Bien-Ly, Maria Hersom, Janice A. Maloney, William J. Meilandt, Daniela Bumbaca, Kapil Gadkar, Kwame Hoyte, Wilman Luk, Yanmei Lu, James A. Ernst, Kimberly Scearce-Levie, Jessica A. Couch, Mark S. Dennis, Ryan J. Watts

  Science Translational Medicine05 Nov 2014 : 261ra154

  Bispecific antibodies engineered to both bind to the primate transferrin receptor and inhibit β-secretase are taken up by the nonhuman primate brain and reduce brain β-amyloid.

  Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
• Share

  Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates

  By Y. Joy Yu, Jasvinder K. Atwal, Yin Zhang, Raymond K. Tong, Kristin R. Wildsmith, Christine Tan, Nga Bien-Ly, Maria Hersom, Janice A. Maloney, William J. Meilandt, Daniela Bumbaca, Kapil Gadkar, Kwame Hoyte, Wilman Luk, Yanmei Lu, James A. Ernst, Kimberly Scearce-Levie, Jessica A. Couch, Mark S. Dennis, Ryan J. Watts

  Science Translational Medicine05 Nov 2014 : 261ra154

  Bispecific antibodies engineered to both bind to the primate transferrin receptor and inhibit β-secretase are taken up by the nonhuman primate brain and reduce brain β-amyloid.

  Share This Article: Copy