Contents

24 September 2014
Vol 6, Issue 255

About The Cover

Cover image expansion

ONLINE COVER A Fingerprint of Surgical Recovery. Comprehensive mapping of the human immune system holds substantial promise to reveal patient-specific immune signatures, which work like fingerprints that predict clinical course and outcomes. Recently developed single-cell mass cytometry allows for both the precise phenotyping of all major immune cells and the assessment of their functional status. Gaudillière et al. have now applied mass cytometry at the bedside to map the immune response to surgical trauma. Engrained in the mobilization of canonical immune signaling networks were patient-specific immune signatures that strongly correlated with the speed of recovery from surgery. [CREDIT: ISTOCKPHOTO/GETTY IMAGES]