PerspectiveCARDIOVASCULAR SCIENCE

Arterial Innervation in Development and Disease

Science Translational Medicine  03 Sep 2014:
Vol. 6, Issue 252, pp. 252ps9
DOI: 10.1126/scitranslmed.3008910

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Abstract

Innervation of arteries by sympathetic nerves is well known to control blood supply to organs. Recent studies have elucidated the mechanisms that regulate the development of arterial innervation and show that in addition to vascular tone, sympathetic nerves may also influence arterial maturation and growth. Understanding sympathetic arterial innervation may lead to new approaches to treat peripheral arterial disease and hypertension.

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