Research ArticleAsthma

Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production

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Science Translational Medicine  02 Jul 2014:
Vol. 6, Issue 243, pp. 243ra85
DOI: 10.1126/scitranslmed.3008961

Article Information

vol. 6 no. 243 243ra85

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 5, 2014
  • Accepted for publication May 6, 2014

Author Information

  1. Gail M. Gauvreau1,
  2. Jeffrey M. Harris2,*,
  3. Louis-Philippe Boulet3,
  4. Heleen Scheerens2,
  5. J. Mark Fitzgerald4,
  6. Wendy S. Putnam2,
  7. Donald W. Cockcroft5,
  8. Beth E. Davis5,
  9. Richard Leigh6,
  10. Yanan Zheng2,
  11. Barbro Dahlén7,
  12. Yehong Wang2,
  13. Romeo Maciuca2,
  14. Irvin Mayers8,
  15. X. Charlene Liao2,
  16. Lawren C. Wu2,
  17. John G. Matthews2 and
  18. Paul M. O’Byrne1
  1. 1McMaster University, Hamilton, Ontario L8N 3Z5, Canada.
  2. 2Genentech Inc., South San Francisco, CA 94080, USA.
  3. 3Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Québec G1V 4G5, Canada.
  4. 4University of British Columbia, Vancouver, British Columbia V5Z 1M9, Canada.
  5. 5University of Saskatchewan, Saskatoon, Saskatchewan S7N 0W8, Canada.
  6. 6University of Calgary, Calgary, Alberta T2N 4Z6, Canada.
  7. 7Karolinska University Hospital, Stockholm S-141 86, Sweden.
  8. 8University of Alberta, Edmonton, Alberta T6G 2G3, Canada.
  1. *Corresponding author. E-mail: harris.jeffrey{at}gene.com

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