Research ArticleCancer

Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship

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Science Translational Medicine  21 May 2014:
Vol. 6, Issue 237, pp. 237ra68
DOI: 10.1126/scitranslmed.3008639

Article Information

vol. 6 no. 237 237ra68

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication January 27, 2014
  • Accepted for publication April 10, 2014

Author Information

  1. Irina M. Shapiro1,
  2. Vihren N. Kolev1,
  3. Christian M. Vidal1,
  4. Yuwaraj Kadariya2,
  5. Jennifer E. Ring1,
  6. Quentin Wright1,
  7. David T. Weaver1,
  8. Craig Menges2,
  9. Mahesh Padval1,
  10. Andrea I. McClatchey3,
  11. Qunli Xu1,
  12. Joseph R. Testa2 and
  13. Jonathan A. Pachter1,*
  1. 1Verastem Inc., Cambridge, MA 02142, USA.
  2. 2Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
  3. 3Massachusetts General Hospital Center for Cancer Research and Department of Pathology, Harvard Medical School, Charlestown, MA 02129, USA.
  1. *Corresponding author. E-mail: jpachter{at}verastem.com

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