FocusBreast Cancer

A Stiffness-Mediated Oncogenic Hammer

Science Translational Medicine  21 May 2014:
Vol. 6, Issue 237, pp. 237fs21
DOI: 10.1126/scitranslmed.3009154

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Abstract

A recent study in Nature Medicine identified a tissue stiffness–induced microRNA that mediates oncogenic signaling; its expression stratifies luminal breast cancer survivors to predict accelerated metastatic relapse.

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