FocusRadiation Toxicity

Reining in Radiation Injury: HIF2α in the Gut

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Science Translational Medicine  14 May 2014:
Vol. 6, Issue 236, pp. 236fs20
DOI: 10.1126/scitranslmed.3009155

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Abstract

Deletion of prolyl hydroxylase domain proteins or overexpression of hypoxia-inducible factor 2α (HIF2α) in the gastrointestinal epithelium improves survival of mice after abdominal irradiation (Taniguchi et al., this issue).

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