Extracorporeal Circulation Without Bleeding

Science Translational Medicine  05 Feb 2014:
Vol. 6, Issue 222, pp. 222fs7
DOI: 10.1126/scitranslmed.3008497

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A newly created antibody to the active site of Factor XIIa protects against clotting of extracorporeal bypass circuitry without bleeding risk in vivo, obviating the need for heparin (Larsson et al., this issue).

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