Research ArticleNanomedicine

Generation of Effector Memory T Cell–Based Mucosal and Systemic Immunity with Pulmonary Nanoparticle Vaccination

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Science Translational Medicine  25 Sep 2013:
Vol. 5, Issue 204, pp. 204ra130
DOI: 10.1126/scitranslmed.3006516

Article Information

vol. 5 no. 204 204ra130

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 3, 2012
  • Accepted for publication July 26, 2013

Author Information

  1. Adrienne V. Li1,2,*,
  2. James J. Moon1,3,4,*,
  3. Wuhbet Abraham2,
  4. Heikyung Suh2,5,
  5. Jamal Elkhader1,
  6. Michael A. Seidman6,
  7. Minmin Yen1,
  8. Eung-Jun Im7,8,
  9. Maria H. Foley1,2,
  10. Dan H. Barouch7,8 and
  11. Darrell J. Irvine1,2,3,5,7,
  1. 1Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.
  2. 2Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA 02139, USA.
  3. 3Department of Materials Science and Engineering, MIT, Cambridge, MA 02139, USA.
  4. 4Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA.
  5. 5Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  6. 6Department of Pathology and Laboratory Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  7. 7Ragon Institute of MGH, MIT and Harvard, Boston, MA 02139, USA.
  8. 8Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  1. Corresponding author. E-mail: djirvine{at}mit.edu
  • * These authors contributed equally to this work.

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