Skinflammation and Drug Toxicity—A Delicate Balance

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Science Translational Medicine  21 Aug 2013:
Vol. 5, Issue 199, pp. 199fs33
DOI: 10.1126/scitranslmed.3006993

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Loss of epidermal growth factor receptor function in epidermal keratinocytes triggers a disfiguring acneiform rash through the coordinate activation of innate and adaptive immune defense mechanisms (Mascia et al. and Lichtenberger et al., this issue).

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