FocusGraft-Versus-Host Disease

One Is Better than Two: TCR Pairing and GVHD

Science Translational Medicine  05 Jun 2013:
Vol. 5, Issue 188, pp. 188fs21
DOI: 10.1126/scitranslmed.3006431

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Abstract

T lymphocytes that express dual TCRs were found more frequently in patients with acute graft-versus-host disease (GVHD) as compared with patients who also underwent allogeneic stem cell transplantation but did not develop acute GVHD (Morris et al., this issue).

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