PerspectiveOPTOGENETICS

From Optogenetic Technologies to Neuromodulation Therapies

Science Translational Medicine  20 Mar 2013:
Vol. 5, Issue 177, pp. 177ps6
DOI: 10.1126/scitranslmed.3003100

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Abstract

The field of optogenetics has provided new insight into neuronal communication and complex brain function. Now, scientists eagerly anticipate clinical application of this technology, with the hope that it will help improve treatments for various neurological disorders. However, the translational hurdles are high. In this Perspective, we highlight the technical, practical, and regulatory hurdles that lie ahead along the path towards making optogenetic neuromodulation therapies a reality in the clinic.

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