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Ovarian Aging: Breaking Up Is Hard to Fix

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Science Translational Medicine  13 Feb 2013:
Vol. 5, Issue 172, pp. 172fs5
DOI: 10.1126/scitranslmed.3005579

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Abstract

Accumulation of double-stranded DNA breaks and inhibition of DNA repair contributes to reproductive aging by diminishing ovarian reserves in mice and women.

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