PerspectiveDrug Discovery

Sisyphus and Translational Stroke Research

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Science Translational Medicine  17 Oct 2012:
Vol. 4, Issue 156, pp. 156ps20
DOI: 10.1126/scitranslmed.3005083

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After more than 1000 failures, we know that our methods for translating effective stroke treatments from the laboratory to the clinic do not work. New preclinical and clinical approaches conceived outside of the current paradigm exist and should be carefully considered. Now, Tymianski and colleagues report on results obtained during translation of a new neuroprotectant.

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