FocusAlzheimer’s Disease

The Nexus of Aβ, Aging, and Sleep

See allHide authors and affiliations

Science Translational Medicine  05 Sep 2012:
Vol. 4, Issue 150, pp. 150fs34
DOI: 10.1126/scitranslmed.3004815

You are currently viewing the abstract.

View Full Text


Roh et al. report a positive feedback loop between sleep-wake irregularities and aggregation of β-amyloid peptide, suggesting that sleep alterations could be an early event in Alzheimer’s disease.


  • Citation: J. R. Gerstner, I. J. Perron, A. I. Pack, The nexus of Aβ, aging, and sleep. Sci. Transl. Med. 4, 150fs34 (2012).

View Full Text