FocusAlzheimer’s Disease

The Nexus of Aβ, Aging, and Sleep

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Science Translational Medicine  05 Sep 2012:
Vol. 4, Issue 150, pp. 150fs34
DOI: 10.1126/scitranslmed.3004815

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Abstract

Roh et al. report a positive feedback loop between sleep-wake irregularities and aggregation of β-amyloid peptide, suggesting that sleep alterations could be an early event in Alzheimer’s disease.

Footnotes

  • Citation: J. R. Gerstner, I. J. Perron, A. I. Pack, The nexus of Aβ, aging, and sleep. Sci. Transl. Med. 4, 150fs34 (2012).

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