LetterMolecular Imaging

Comment on “Rapid Cancer Detection by Topically Spraying a γ-Glutamyltranspeptidase–Activated Fluorescent Probe”

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Science Translational Medicine  15 Feb 2012:
Vol. 4, Issue 121, pp. 121le1
DOI: 10.1126/scitranslmed.3003686

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A recent report from Urano et al. described the development of near-infrared (NIR) probes for cancer detection using chemical bioconjugation of targeting agents. Here, I highlight an alternative strategy to develop cancer-selective NIR imaging and theranostic agents without chemical conjugation.

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