PerspectiveCancer Genomics

Understanding the Enemy

Science Translational Medicine  31 Aug 2011:
Vol. 3, Issue 98, pp. 98ps37
DOI: 10.1126/scitranslmed.3003001

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In this issue of Science Translational Medicine, Tanas and colleagues describe a disease-defining genetic alteration for the vascular cancer epithelioid hemangioendothelioma (EHE). The resulting EHE-associated fusion gene encodes an aberrantly expressed putative transcription factor. This molecular information is the latest in a series of genetic discoveries that aid in cancer diagnosis and may pave the way to targeted therapeutic agents.


  • Citation: V. E. Velculescu, L. A. Diaz Jr., Understanding the Enemy. Sci. Transl. Med. 3, 98ps37 (2011).

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