PerspectivePediatric Vaccines

Development of Newborn and Infant Vaccines

Science Translational Medicine  06 Jul 2011:
Vol. 3, Issue 90, pp. 90ps27
DOI: 10.1126/scitranslmed.3001880

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Vaccines for early-life immunization are a crucial biomedical intervention to reduce global morbidity and mortality, yet their developmental path has been largely ad hoc, empiric, and inconsistent. Immune responses of human newborns and infants are distinct and cannot be predicted from those of human adults or animal models. Therefore, understanding and modeling age-specific human immune responses will be vital to the rational design and development of safe and effective vaccines for newborns and infants.


  • Citation: G. Sanchez-Schmitz, O. Levy, Development of newborn and infant vaccines. Sci. Transl. Med. 3, 90ps27 (2011).

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