Contents

06 July 2011
Vol 3, Issue 90

About The Cover

Cover image expansion

ONLINE COVER Bicycle Built for All. Like the challenging terrains of Le Tour de France, the road to new therapeutics, diagnostics, and devices is tortuous. The U.S. National Institutes of Health (NIH) is in the process of designing a new vehicle—a reengineered translational enterprise—to speed the journey toward improved clinical medicine. At the heart of this effort is the newly envisioned National Center for Advancing Translational Sciences (NCATS). Shown here as the hub of a bicycle wheel (in orange), NCATS will serve as a coordinating nucleus for the wheel's spokes—a diverse collection of stakeholders including NIH institutes and centers, the U.S. Food and Drug Administration, academic medical centers, biotech and pharma, patient groups and foundations. With the hub and spokes properly aligned, the wheel moves the vehicle forward. In this week's Commentary, NIH Director Francis Collins outlines his vision of how NCATS will help to reengineer the process of biomedical translation. [CREDIT: C. BICKEL/SCIENCE TRANSLATIONAL MEDICINE]