PerspectiveMetabolic Disease

Receptor Antibodies as Novel Therapeutics for Diabetes

Science Translational Medicine  14 Dec 2011:
Vol. 3, Issue 113, pp. 113ps47
DOI: 10.1126/scitranslmed.3003447

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Abstract

Antibodies to receptors can block or mimic hormone action. Taking advantage of receptor isoforms, co-receptors, and other receptor modulating proteins, antibodies and other designer ligands can enhance tissue specificity and provide new approaches to the therapy of diabetes and other diseases.

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